Arab Health Conference 2021: Helicobacter pylori – the Evolution of Treatment Protocols
Released on : Jul. 28, 2023
Link: https://drive.google.com/file/d/1otTqVmspgVXYYXRxu3KuXm_SiOSGo_rX/view?ts=64bdfbbd
Dr. Warren and Professor Marshall’s discovery of Helicobacter pylori and its link to peptic ulcers won them the Nobel Prize in 2005.
Once discovered, treatment of H. pylori in the stomach was found to only be achieved through precision antibiotic therapy.
The ‘Marshall Plan’ for treatment of H. pylori is as follows.
Step 1. Choose a base therapy that is not resistance inducing.
This is done using one or two of the following:
- Proton pump inhibitor (PPI) or any strong acid blocker
- Strong bismuth dose
- Amoxicillin
- Tetracycline
In order for treatment to be effective it was found that a PPI or a strong acid blocker was essential for a high eradiation rate to be achieved.
Step 2. Choose a ‘CIDAL’ antibiotic (or two)
- Clarithromycin
- Metronidazole
- Levofloxacin
- Rifabutin
Do not repeat failed antibiotic treatments.
Step 3. Always check for treatment success
Tests that can assess H. pylori presence:
1. C14-UBT
- Safe, simple and quick
- Tri-Med PYtest
- Tri-Med CLOtest
2. C13-UBT
- Safe, complicated and slower than C14-UBT
For further information and to watch Professor Marshall’s presentation at the Arab Health Conference, Helicobacter pylori – the Evolution of Treatment Protocols, please click on the link below.
Link: https://drive.google.com/file/d/1otTqVmspgVXYYXRxu3KuXm_SiOSGo_rX/view?ts=64bdfbbd